Toji Fushiguro is a former member of the Zen'in Clan, he is known as the "Sorcerer Killer" and is the father of Megumi. Like Maki, he was born with a Heavenly Restriction, rendering him unable to use Cursed Techniques. In exchange, he was given immense physical prowess, and his senses reached a point where he could still interact with Cursed Spirits. His lack of Cursed Energy allows him to sneak up on and kill Jujutsu Sorcerers, and his Inverted Spear of Heaven allows him to bypass any Cursed Technique. He defeated Gojo and Geto on their first encounter, bringing Gojo to the brink of death. He is callous and has little regard for his own family, selling Megumi to the Zen'in Clan for money and even forgetting his name. However in his dying moments he asks Gojo to protect Megumi from being sold.

Satoru Gojo is a sorcerer working as a teacher at the Tokyo Prefectural Jujutsu High School. He wields the Six Eyes (六眼, Rikugan), which minimizes Cursed Energy consumption and enhances perception, and the Limitless (無下限, Mukagen) technique, granting atomic-level control over space. Limitless includes: Infinity (無限, Mugen) (infinite slowing of incoming objects), Cursed Technique Lapse: Blue (術式 順転 蒼, Jutsushiki Junten Ao) (a converging void that crushes targets), Cursed Technique Reversal: Red (術式 反転 赫, Jutsushiki Hanten Aka) (a repelling force from reversed Cursed Energy), and Hollow Technique: Purple (虚式 茈, Kyoshiki Murasaki) (a destructive fusion of Blue and Red that annihilates matter). His Domain Expansion, Unlimited Void (無量空処, Muryōkūsho), floods targets with infinite information, immobilizing them.

Ryomen Sukuna, also known as the King of Curses, is one of the two main antagonists (alongside Kenjaku) of the manga/anime series Jujutsu Kaisen. He is the master of Uraume, the "twin brother" of Wasuke Itadori, and the arch-nemesis of his "grandnephew" Yuji Itadori and Satoru Gojo. Having lived in jujutsu's golden age, the Heian Era, Sukuna is widely known and feared as the strongest jujutsu sorcerer in history. A thousand years ago, he has turned himself into a cursed object by transferring his soul into his twenty indestructible fingers. He is resurrected into modern times when Yuji Itadori eats one of those fingers, making him able to possess the boy's body. It is later revealed that Wasuke Itadori, Yuji's grandfather, was the reincarnation of Sukuna's twin brother, making Yuji his "grandnephew" and descendant. This also explains why Sukuna is incapable of possessing Yuji's whole body at will.